Haoma Revelation Aid
Haoma was served in meditative rituals to experience death before dying so as to discover otherworldly wisdom and achieve a sublime state of mind. Magi’s team of Ph.D. scientists and ethnopharmacologists formulated Haoma Revelation Aid to bring this profoundly insightful experience in a macrodose psychoactive supplement for those who commit themselves to the work of intentional preparation for personal insight.
“Homage to Haoma, that so elevates the mind of a poor man, that he gets enlightened through knowledge.” – passage from Zoroastrian Texts
- Haoma Revelation Aid is a natural psychoactive supplement known as Oneirogen, formulated to contain a precise macrodose of select Espand-derived beta-carbolines that put the mind into a dream-like waking state.
- Haoma Revelation Aid is all-natural and non-habit-forming.
- Tap into the realm of the unconscious to explore what’s out there that we have no control over.
PREPARATION AND DOSEThis macrodose demands conscientious and thoughtful preparation of mindset and setting. Minimize consumption of fermented, canned, and aged foods including cheeses, cured meats, and kombucha for at least 24 hours prior to this psychoactive journey. For best results, fast for at least 12 hours prior to your journey. See below for a detailed list of dietary abstinence recommendations. Set your intention mindfully about what you wish to discover about yourself. Choose a serene and familiar environment where you can sit or lie in comfort, and feel safe and quiet with minimal external stimulation. Take 1 capsule, close your eyes, and begin to meditate. Close your eyes and begin to meditate in any form that is calm, e.g. open awareness like Vipassana or fixed attention like Transcendental Meditation, but not any form that is physically intensive like holotropic breathwork or Zikr. You should begin to feel your mind spreading and lightening further as you get deeper into meditation, around 5-15 minutes after dosage. The peak effects will kick in around 30-60 minutes after dosage, depending upon how empty is your stomach and how tranquil is your mind. The main effects will begin to dissipate 2-4 hours after dosage for you to return to normal waking activities. Wait at least 3 days before you take another macro dose. Trust the wisdom of our Ancestors. Trust yourself, your preparation, and your dedication as you embark on a journey of self-discovery and omniscience. Unlock boundless possibilities with unwavering confidence in the profound potential of this plant-based wisdom, the ancestral legacy of Zoroastrian Magi. Do not exceed the recommended dose. Do not take if you are pregnant or nursing. Consult with your physician prior to use if you have high blood pressure or a medical condition, or if you take any prescription medications (including but not limited to MAO inhibitors and antidepressants). Do not operate motor vehicles or machinery while under the effects of Haoma Revelation Aid. Store in a cool, dry place. Keep out of reach of children.
FOODS TO AVOIDTyramine is a naturally occuring amino acid produced in the body that helps regulate blood pressure and can also be found in high concentrations in certain foods, particularly aged, canned, and fermented foods . Monoamine oxidase inhibitors (MAOI’s) that inhibit the breakdown of neurotransmitters such as serotonin and dopamine also inhibit the breakdown of tyramine, and can present a risk of tyramine-related hypertension. Because of this risk, both modern and ancestral cultures have followed a practice of exercising dietary caution when ingesting MAOI’s, including natural MAOIs such as beta-Carbolines. This includes the medical advice of avoiding tyramine-rich foods when taking prescription MAOI’s such as Marplan (isocarboxid), and the tradition of following a preparatory Ayahuasca dieta before a ceremony. The risk of tyramine related hypertension is much less of a concern today than 30 years ago when food was much higher in tyramine, but scientific research suggests that the risk of tyramine related hypertension continues to affect 15% of the population. For the other 85%, there is lesser concern when combining MAOI’s with tyramine at levels up to 200-800mg (equivalent to eating 1lb of gouda cheese or 1.5lbs of mackerel – two of the highest tyramine-containing foods). But for the other 15%, there may be a concern at as low as 10mg of tyramine (equivalent to 2 ounces of ham or 1 ounce of cheddar – two of the higher tyramine-containing foods). Very few in Magi’s community follow an MAOI diet and none have reported any issues. Regardless, we recommend taking our products either first thing in the morning or last thing in the evening on an empty stomach to mitigate this concern – and more importantly for greater effectiveness. The majority of your body’s neurotransmitters are actually in the gut, not the brain, so consumption on an empty stomach also helps with bioavailability. Especially with Haoma Revelation Aid, which contains a significantly higher content of beta-Carbolines than our mini-dose and microdose products, we also recommend avoiding the following tyramine-rich foods for 24 hours before and after:
- Aged cheeses, particularly blue cheese, cheddar, swiss, paresan, and feta.
- Cured or processed meats, including dried sausages, pepperoni, hot dogs, bologna, bacon, and prosciutto.
- Pickled or fermented vegetables, such as kimchi, pickles, and sauerkraut.
- Fermented soy-based products such as tofu, soy sauce, and miso soup.
- Fermented beverages, including alcohol and kombucha.
- MSG-containing foods and sauces, such as fish sauce and teriyaki.
- Dried fruits and vegetables.
- Any canned or bottled foods.
- Yeast-extracts such as vegemite, marmite, and sourdough bread.
- Aged meats, particularly red meat.
- Aged fishes, such as smoked salmon, mackerel, cod, and sardines.
- Certain beans, such as fava and broad beans.
- Nuts, seeds, and nut butters
How will I feel after taking Haoma Revelation Aid?
- Most people report feeling a warm numbness and relaxing feeling of mental spreading within 15 minutes after taking Haoma Revelation Aid, with some physiological disorientation. Some in our community have described the sensation as similar to a strong dose of yagé, the ayahuasca vine, in the absence of chacruna (the DMT source commonly used in ayahuasca brew).
- Most people report that the peak psychological and emotional effects of Haoma Revelation Aid persist for 1-2 hours, and the lingering relaxing and opening sensation continues for as long as 4-6 hours. The physiological effects persist for 2-3 hours, after which most people feel re-oriented and capable of social interaction or operating motor vehicles again.
Should I meditate on Haoma Revelation Aid?
- Yes! Haoma Revelation Aid is meant to facilitate deep personal exploration and insight, as facilitated by the meditative state of conscious awareness.
- Haoma Revelation Aid is well suited for any form of meditation that is serene and calm, such as open awareness like Vipassana or fixed attention like Transcendental Meditation. It is not well suited for a physically intensive form of meditation like holotropic breathwork or Zikr.
Can I take Haoma Revelation Aid day or weekly?
- Haoma Revelation Aid should not be taken daily. It can be safely taken weekly, but we do not recommend using Haoma Revelation Aid more than once every two weeks. The psychological effects of deep personal insights can be overwhelming, and at a minimum require intentional integration to be internalized.
Why is it best to take Haoma Revelation Aid on an empty stomach?
- The majority of your body’s neurotransmitters are in the gut, not the brain. For this reason we recommend taking Haoma Revelation Aid in the morning before eating, as food can interfere with neurotransmitter absorption. While this is not a requirement, the closer your stomach is to empty, the higher the bioavailability.
Is Haoma Revelation Aid safe?
- Haoma Revelation Aid is safe when taken as directed at the recommended dosage.
- We designed our Haoma® formula from the purified natural plant extracts of Espand. In addition to their anti-inflammatory and neuroprotective properties, the natural beta-Carbolines extracted from Espand also function as monoamine oxidase inhibitors (MAOIs)  that can cause an increase in blood pressure when consuming foods containing tyramine .
- The levels of tyramine in food have been decreasing over time, thanks to advancements in agricultural technology and improvements in food processing and storage. Although tyramine related hypertension affects only a small minority of the population , we recommend avoiding tyramine-rich foods when taking Haoma Revelation Aid. Taking Haoma Revelation Aid on an empty stomach will also mitigate the risk of hypertension and nausea.
How does it work?
- Our macrodose supplement contains Haoma (R), a precise macrodose formulation of Espand-derived beta-Carbolines that begin to affect the central nervous system within 20 minutes of being ingested. The compounds in Haoma(R) have been shown to:
- Inhibit neurotoxins  and provide neuroprotective antioxidant effects 
- Inhibit tumor cells  and promote the growth of anti-tumor cytokines 
- Inhibit inflammatory signaling5 and the growth of inflammatory prostaglandins 
- Promote neurogenesis by increasing BDNF6 and hNPC levels7
- Modulate neuroreceptors such as serotonin, dopamine, acetylcholine, histamine, and imidazoline, that are involved in perception and consciousness 
- Modulate the brain’s limbic system that is involved in semantic memory storage and emotional processing to slow the level of switching between states of fear and security.
- At its dosage level and precise blend of specific beta-Carbolines our Haoma(R) formula promotes the an altered state of perception for cognitive insight while awake.
Haoma – The Divine Elixir of Truth
- Haoma, the divine elixir of truth, dates back to 2000 BCE as documented in both Zoroastrian Avestan texts as well as Hindu texts such as the Rig Veda. It is believed to have been created by Ahura Mazda, the supreme god, and consumed to ward off evil, grant immortality, and uncover the secrets of life after death.
- Similar to other sacred brews such as Ayahuasca, dating back 1,000 years ago to the Amazonian basin, and Kykeon, consumed by early Christians at Eleusis from as far back as 4th century BCE, Haoma was also a mixture of plants consumed in the Zoroastrian religious rituals to connect with the divine and achieve spiritual enlightenment.
- The identity of Haoma has been debated for years. Gordon Wasson famously published his belief that its identity was Amanita muscaria mushrooms, although this species is not indigenous to the Iranian plateau. Furthermore, the linguistic root of haoma, or hom, refers to a ritual pressing, which is not involved in the preparation of an Amanita muscaria brew (boiling). Based upon its legendary yellow/green color; the subjective description of Haoma-induced trance from the book of Arda Viraf, one of the most important Zoroastrian texts; and preparation that requires pressing of plant matter, we at Magi Ancestral Supplements agree with the scholar David Flattery who concluded that the key ingredient in Haoma is Espand.
Espand – Holy Plant Wisdom
- The key ingredient in Haoma Revelation Aid is Espand, also known as Syrian Rue or Peganum Harmala. Espand is an abundant source of beta-carbolines , a class of naturally occurring organic compounds with psychoactive and neuroprotective properties . Beta-carbolines are found naturally in a few plants, including Espand (P. Harmala) and Yage (B. Caapi), the ancestral Amazonian plant that is the main ingredient in the psychedelic brew Ayahuasca . Thanks to modern science, we now understand the neurochemistry behind our ancestors’ discoveries thousands of years ago.
- We formulated Haoma Revelation Aid to contain approximately the same beta-carboline content as found in a standard dose of Haoma or Ayahuasca.
Beta-Carbolines – Ancestral Secret to Neurological Health
Beta-carbolines such as harmine  are unique neuromodulators that have been shown to exhibit anti-inflammatory activity in neurons  and promote neurogenesis by increasing levels of brain-derived neurotrophic factor (BDNF)  and human neural progenitor cells (hNPC) .
Beta-carbolines also interact with the sleep cycle via the pineal gland, the part of the brain that regulates the body’s circadian rhythm. The pineal gland regulates the sleep cycle via the synthesis of melatonin from serotonin (the “happiness hormone”) , and is also believed to produce both beta-carbolines and the psychedelic compound DMT (the “spirit molecule”) via alternate pathways .
Beta-Carbolines Macrodose – Translational Neuroscience
All of Magi Ancestral Supplements’ products contain beta-Carbolines, but Haoma Revelation Aid is our only product that is formulated with a macrodose quantity of Espand-derived beta-Carbolines, and in an alkaloid ratio (e.g. harmine, harmaline, tetrahydroharmine, harmalol, etc.) that is meant to facilitate an altered state of perception for cognitive insight while awake.
Three neuroscience markers that are commonly used to assess altered states of consciousness are:
- Whole Brain Synchronicity, a measure of total electrical activity spatially across the brain, that is correlated with coordinated thought processing and activity
- Cognitive Insight Synchronicity, a measure of Gamma frequency wavelength spatially across the brain that is correlated with higher level thought (e.g. problem-solving, the aha moment)
- Cognitive Entropy, a measure of brain wavelength variability that is correlated with new thought patterns, such as belief structures and habits (e.g., new neural pathways)
The above chart characterizes these neuroscience markers and their translational subjective effect under a few comparative conditions:
- Awake, with meditation as a baseline activity.
- Dreaming, particularly stage 4 lucid dreaming: characterized by high Insight Synchronicity with the experience of observing in discovery.
- Psychedelic Experience, with a formulation such as ayahuasca that combines both a tryptamine (e.g. DMT, psilocybin) and beta-Carbolines: Characterized by high Insight Synchronicity and Entropy with the experience of participating in discovery through the rush of chaotic thoughts and memories.
- Psychoactive Experience, with Haoma Revelation Aid: Characterized by high Insight Synchronicity but low Entropy, in the absence of a tryptamine, with the experience of participating in discovery calmly, with the absence of a chaotic rush of thoughts and memories.
We formulated Haoma Revelation Aid to provide a calmer and more controlled experience than a full psychedelic journey, but with noticeable psychological and physiological effects in pursuit of deep revelatory insights.
-  Mckenna, Dennis J., et al. “Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca.” Journal of Ethnopharmacology, vol. 10, no. 2, Apr 1984, pp 195-223. https://doi.org/10.1016/0378-8741(84)90003-5
-  McCabe, Beverly J. “Dietary tyramine and other pressor amines in MAOI regimens: A review.” Journal of the American Dietetic Association, vol.86, no. 8, Aug 1986, pp. 1059-1064.
-  Edwards, Bradley , Denise M. O’Driscoll, et al. “Aging and Sleep:” Physiology and Pathophysiology.” Seminars in Respiratory and Critical Care MEdicine, vol. 31, no. 5 16 Nov 2012, pp. 618-633. https://www.sciencedirect.com/science/article/abs/pii/S0889157505001444
-  Herraiz, Tomás, and Hugo Guillén. “Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.” Food and Chemical Toxicology, 2011 Aug;49(8):1773-81. doi: 10.1016/j.fct.2011.04.026.
-  Samoylenko, Volodymyr, et al. “Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson’s disease.” Journal of Ethnopharmacology, vol. 127, no. 2, Feb 2010, pp. 357-367.
-  Bikadar, SM, et al. “Cerebroprotective effect of isolated harmine alkaloids extracts of seeds of Peganum harmala L. on sodium nitrite-induced hypoxia and ethanol-induced neurodegeneration in young mice.” Pakistan Journal of Biological Sciences, 01 Dec 2013, 16(23):1687-1697. DOI: 10.3923/pjbs.2013.1687.1697
-  Hamsa, T.P., and Girija Kuttan. “Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro.” European Journal of Pharmacology, 2010 Dec 15;649(1-3):64-73. doi: 10.1016/j.ejphar.2010.09.010.
-  Moloudizargari, Milad, et al. “Pharmacological and therapeutic effects of Peganum harmala and its main alkaloids.” Pharmacognosy Reviews, 2013 Jul-Dec; 7(14): 199–212. doi: 10.4103/0973-7847.120524
-  Kyzar, Evan J., et al. “Psychedelic Drugs in Biomedicine.” Trends in Pharmacological Sciences, vol. 38, no. 11, Nov 2017, pp. 992-1005. https://doi.org/10.1016/j.tips.2017.08.003
-  Airaksinen, MM, and Kari I. “Beta-carbolines, psychoactive compounds in the mammalian body. Part I: Occurrence, origin and metabolism.” Medical Biology. 1981 Feb;59(1):21-34. PMID: 7022042.
-  Frost, Danielle, et al. “β-Carboline Compounds, Including Harmine, Inhibit DYRK1A and Tau Phosphorylation at Multiple Alzheimer’s Disease-Related Sites.” PLoS ONE 6(5): e19264, May 2011.
-  Dennis J McKenna,”Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges.” Pharmacology & Therapeutics, Volume 102, Issue 2, 2004, pp. 111-129.
-  Berrougui, Hicham, et al. “Protective effects of Peganum harmala L. extract, harmine and harmaline against human low-density lipoprotein oxidation.” Journal of Pharmacy and Pharmacology, Volume 58, Issue 7, July 2006, pp. 967–974
-  Liu, Xin, et al. “Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling.” Biochemical and Biophysical Research Communications, Jul 2017, pp. 489(3):332-338. doi: 10.1016/j.bbrc.2017.05.126
-  Dos Santos, Rafael G., and Jaime E.C. Hallak. “Effects of the Natural β-Carboline Alkaloid Harmine, a Main Constituent of Ayahuasca, in Memory and in the Hippocampus: A Systematic Literature Review of Preclinical Studies.” Journal of Psychoactive Drugs, vol. 49, no. 1, Dec 2016. https://doi.org/10.1080/02791072.2016.1260189
-  Dakic Vanja, et al.”Harmine stimulates proliferation of human neural progenitors.” PeerJ, 2016 Dec 6;4:e2727. doi: 10.7717/peerj.2727
-  Wu, Ying-Hui, and Dick F. Swaab. “The human pineal gland and melatonin in aging and Alzheimer’s disease.” Journal of Pineal Research, Dec 2004.
-  Dean, Jon G., et al. “Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain.” Scientific Reports, Jun 2019, 9333
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This was unlike anything I had ever tried. Completely grounded in reality with the ego subdued just enough to make the experience joyful, peaceful and therapeutic . It was very gentle. I am looking forward to going deeper with this medicine. Highly recommend.
I heard about this from my favorite podcast, Rune Soup. I was very excited to try it because I had made a Syrian Rue decoction many years ago and enjoyed the experience except for the awful taste and stomach upset. But I wasn't thrilled with the strength of the product, it was barely noticeable in my 3+ hour meditation and ritual session. I felt slightly simulated and able to meditate for longer but nothing much beyond that. For the price, and after the descriptions on the podcast I expected a little more. I'll still be trying the second capsule as a potentiator for other medicine but I don't think I'll buy this product again until the price comes down more.
I think the work Ancestral Magi are doing is so important but they need to offer a stronger product at a better price. I'm sure this is challenging in today's economy but it should be strived for nonetheless. Thanks