Beta-Carbolines – Ancestral Secret to Neurological Health
Beta-carbolines such as harmine [13] are unique neuromodulators that have been shown to exhibit anti-inflammatory activity in neurons [14] and promote neurogenesis by increasing levels of brain-derived neurotrophic factor (BDNF) [15] and human neural progenitor cells (hNPC) [16].
Beta-carbolines also interact with the sleep cycle via the pineal gland, the part of the brain that regulates the body’s circadian rhythm. The pineal gland regulates the sleep cycle via the synthesis of melatonin from serotonin (the “happiness hormone”) [17], and is also believed to produce both beta-carbolines and the psychedelic compound DMT (the “spirit molecule”) via alternate pathways [18].
Dreams that are complex and immersive tend to occur during the REM stage of the sleep cycle [19]. REM sleep is characterized by brainwave patterns that are similar to that of the awake state, in particular, high-frequency beta and gamma brainwaves that are associated with insight and connectivity [20]. Supplementation with Mang Lucid Dream Aid has been shown in individuals to increase high-frequency brain patterns during the REM stage of sleep, promoting lucidity and recall of vivid dreams.
Brainwave Activity during the 1st REM Sleep Cycle Onset
Left: Prior to Mang Lucid Dream Aid | Right: After 5 Days with Mang Lucid Dream Aid
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