Ushta Mood Boost Supplement
$55.00
Ushta Mood Boost Supplement is natural stress relief supplement that is formulated with natural extracts of Espand, an ancestral plant that has been used by the Pagan and Zoroastrian priests of ancient Iran in pursuit of otherworldly wisdom and a sublime state of mind; and Suan Zao Ren, an important plant used for more than 2,000 years in the pharmacopeia of Traditional Chinese Medicine. Magi’s team of PhD scientists and ethnopharmacologists formulated Ushta Mood Boost Supplement to provide a safe, effective, and natural mood booster for stress relief.
“Today I escaped anxiety. Or no, I discarded it, because it was within me, in my own perceptions, not outside.” – Marcus Aurelius
- Ushta Mood Boost Supplement is formulated to contain a precise minidose of select Espand-derived beta-carbolines and Suan Zao Ren-derived antioxidants that invoke a feeling of calmness, empathy, and openness.
- Ushta Mood Boost Supplement is all-natural and non habit-forming.
- Achieve a pleasant state of bliss from within by deepening your empathy for yourself.
Product Description
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Instructions
- Take up to one capsule per day as needed.
- Do not exceed the recommended daily dose. Do not take if you are pregnant or nursing. Consult with your physician prior to use if you have high blood pressure or a medical condition, or if you take any prescription medications (including but not limited to MAO inhibitors and antidepressants).
- Store in a cool, dry place. Keep out of reach of children.
FAQ
How will I feel after taking Ushta Mood Boost Supplement?
- Most people report feeling light, calm, open, and empathetic, within 15 minutes after taking Ushta Mood Boost Supplement without physiological effects, and with the sensation lasting all-day. Some in our community have described the sensation as similar to microdosing a consistent standardized dose of Ayahuasca.
- Ushta Mood Boost Supplement is not formulated for productivity, but most people report feeling more productive at work due to increased feelings of openness, social empathy, and self kindness.
Should I meditate on Ushta Mood Boost Supplement?
- Meditation is not necessary to achieve the benefits of Ushta Mood Boost Supplement, it’s generally good advice to always get more meditation.
- Meditation on Ushta Mood Boost Supplement will enable a warm and empathetic meditation sensation that is a good fit for loving kindness meditation. Whereas the sensation of non-focus and introspection facilitated by Stard Deep Meditation supplement is uniquely suited for meditation, Ushta Mood Boost Supplement can be taken in any context.
Can I take Ushta Mood Boost Supplement every day?
- We designed Ushta Mood Boost Supplement so that you can take it safely every day without becoming dependent: as part of a daily habit, preemptively before a stressful or socially-demanding engagement, or on-demand in response to feelings of anxiety.
Why is it best to take Ushta Mood Boost Supplement on an empty stomach?
- The majority of your body’s neurotransmitters are in the gut, not the brain. For this reason we recommend taking Ushta Mood Boost Supplement in the morning before eating, as food can interfere with neurotransmitter absorption/metabolization. While this is not a requirement, the closer your stomach is to empty, the higher the bioavailability.
Is Ushta Mood Boost Supplement safe?
- Ushta Deep Meditation Supplement is safe when taken as directed at the recommended dosage.
- We designed our Ushta® formula from the purified natural plant extracts of Espand and Suan Zao Ren. In addition to their anti-inflammatory and neuroprotective properties, the natural beta-Carbolines extracted from Espand also function as monoamine oxidase inhibitors (MAOIs) [1] that can cause an increase in blood pressure when consuming foods containing tyramine [2].
- The levels of tyramine in food have been decreasing over time, thanks to advancements in agricultural technology and improvements in food processing and storage. Although tyramine related hypertension affects only a small minority of the population [3], we recommend avoiding tyramine-rich foods when taking Ushta Mood Boost Supplement. Taking Ushta Mood Boost Supplement on an empty stomach will also mitigate the risk of hypertension and nausea.
How does it work?
- Our Mood Boost Supplement contains Ushta®, a precise minidose formulation of Espand-derived beta-Carbolines and Suan Zao Ren-derived antioxidants that begin to affect the central nervous system within 20 minutes of being ingested. The compounds in Ushta® have been shown to:
- Inhibit neurotoxins [4] and provide neuroprotective antioxidant effects [5]
- Inhibit tumor cells [6] and promote the growth of anti-tumor cytokines [7]
- Inhibit inflammatory signaling [5] and the growth of inflammatory prostaglandins [8]
- Promote neurogenesis by increasing BDNF [6] and hNPC levels [7]
- Modulate neuroreceptors such as serotonin, dopamine, acetylcholine, histamine, and imidazoline, that are involved in perception and consciousness [9]
- Modulate the brain’s limbic system that is involved in semantic memory storage and emotional processing to slow the level of switching between states of fear and security.
- Through these actions, Ushta® formula promotes stress relief and feelings of empathy, openness, and kindness.
Ancestral Philosophy
Espand – Holy Plant Wisdom
- Ushta refers to a state of bliss achieved by those who pursue truth for the righteousness of truth itself. We created Ushta Mood Boost Supplement with the inspiration of achieving bliss by calming the stresses and anxieties that we humans are prone to limit ourselves with.
- The key ingredient in Ushta Mood Boost Supplement is Espand, also known as Syrian Rue or Peganum Harmala. Espand is an abundant source of beta-carbolines [10] , a class of naturally occurring organic compounds with psychoactive and neuroprotective properties [11]. Beta-carbolines are found naturally in a few plants including Espand (P. Harmala) and Yage (B. Caapi), the ancestral Amazonian plant that is the main ingredient in the psychedelic brew Ayahuasca [12] . Thanks to modern science, we now understand the neurochemistry behind what our ancestors discovered thousands of years ago.
Suan Zao Ren – Elixir of Life
- Ushta Mood Boost Supplement is also formulated with the natural extracts of Suan Zao Ren, an important plant used for more than 2,000 years in the pharmacopeia of Traditional Chinese Medicine for the treatment of anxiety and insomnia. Suan Zao Ren is referred to as the elixir of life, as the folkloric mantra goes “three a day keeps you young forever.”
- Suan Zao Ren contains a high level of antioxidants that affect the brain’s GABA receptors and are known to affect feelings of calm and anxiety by interacting with the brain’s limbic system that is involved with semantic (long-term) memory storage and emotional processing (citation). These antioxidants in Suan Zao Ren synergistically amplify the mood, focus, and empathy-boosting effects of Espand-derived beta-Carbolines in combination.
Pharmaceutical Science
Beta-Carbolines – Ancestral Secret to Neurological Health
Beta-carbolines such as harmine [13] are unique neuromodulators that have been shown to exhibit anti-inflammatory activity in neurons [14] and promote neurogenesis by increasing levels of brain-derived neurotrophic factor (BDNF) [15] and human neural progenitor cells (hNPC) [16].
Beta-carbolines also interact with the sleep cycle via the pineal gland, the part of the brain that regulates the body’s circadian rhythm. The pineal gland regulates the sleep cycle via synthesis of melatonin from serotonin (the “happiness hormone”) [17], and is also believed to produce both beta-carbolines and the psychedelic compound DMT (the “spirit molecule”) via alternate pathways [18].
Meditation is characterized by mid-frequency alpha brainwaves that are correlated with non-directive attention and alertness in waking states. Supplementation with a precise dose of beta-Carbolines such as in Stard Deep Meditation supplement has been shown in individuals to increase mid-frequency alpha brainwaves during physically inactive forms of meditation (e.g. Vipassana Open Awareness, Transcendental Fixed Attention).
Espand + Suan Zao Ren – Plant Synergies
The GABA-modulating antioxidants in Suan Zao Ren have been shown to induce feelings of calm and anxiety by interacting with the brain’s limbic system that is involved with semantic (long-term) memory and emotional processing.
Research has shown that stress is characterized by high theta-gamma wavelength synchronicity in the basolateral amygdala region of the limbic system (footnote). This pattern is thought to characterize rapid emotional switching between states of fear and safety. Antioxidants derived from Suan Zao Ren have been shown to decrease theta-gamma wavelength synchronicity in the basolateral amygdala, contributing towards feelings of lesser emotional switching from semantic memory recall.
Ushta Mood Boost Supplement is formulated with a precise combination of Espand-derived beta-Carbolines and Suan Zao Ren-derived extracts in order to produce the synergistic effect of these two plants, and has been shown in individuals during meditation to:
- Increase mid-frequency alpha brainwaves
- Decrease theta-gamma wavelength synchronicity in the basolateral amygdala
Brainwave Activity: 15 minutes of Open Awareness Meditation
Without Ushta Mood Boost Supplement |
With Ushta Mood Boost Supplement |
1) Alpha Power measured as the ratio of electrical activity in the alpha frequency band compared to total electrical activity
2) Theta-Gamma Synchronicity measured as the correlation coefficient between theta frequency band and gamma frequency band wavelengths across the meditation period
References
- [1] Mckenna, Dennis J., et al. “Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca.” Journal of Ethnopharmacology, vol. 10, no. 2, Apr 1984, pp 195-223.
- [2] McCabe, Beverly J. “Dietary tyramine and other pressor amines in MAOI regimens: A review.” Journal of the American Dietetic Association, vol.86, no. 8, Aug 1986, pp. 1059-1064.
- [3] Edwards, Bradley , Denise M. O’Driscoll, et al. “Aging and Sleep:” Physiology and Pathophysiology.” Seminars in Respiratory and Critical Care MEdicine, vol. 31, no. 5 16 Nov 2012, pp. 618-633.
- [4] Herraiz, Tomás, and Hugo Guillén. “Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.” Food and Chemical Toxicology, 2011 Aug;49(8):1773-81.
- [5] Samoylenko, Volodymyr, et al. “Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson’s disease.” Journal of Ethnopharmacology, vol. 127, no. 2, Feb 2010, pp. 357-367.
- [6] Bikadar, SM, et al. “Cerebroprotective effect of isolated harmine alkaloids extracts of seeds of Peganum harmala L. on sodium nitrite-induced hypoxia and ethanol-induced neurodegeneration in young mice.” Pakistan Journal of Biological Sciences, 01 Dec 2013, 16(23):1687-1697.
- [7] Hamsa, T.P., and Girija Kuttan. “Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro.” European Journal of Pharmacology, 2010 Dec 15;649(1-3):64-73
- [8] Moloudizargari, Milad, et al. “Pharmacological and therapeutic effects of Peganum harmala and its main alkaloids.” Pharmacognosy Reviews, 2013 Jul-Dec; 7(14): 199–212. doi: 10.4103/0973-7847.120524
- [9] Kyzar, Evan J., et al. “Psychedelic Drugs in Biomedicine.” Trends in Pharmacological Sciences, vol. 38, no. 11, Nov 2017, pp. 992-1005. https://doi.org/10.1016/j.tips.2017.08.003
- [10] Airaksinen, MM, and Kari I. “Beta-carbolines, psychoactive compounds in the mammalian body. Part I: Occurrence, origin and metabolism.” Medical Biology. 1981 Feb;59(1):21-34. PMID: 7022042.
- [11] Frost, Danielle, et al. “β-Carboline Compounds, Including Harmine, Inhibit DYRK1A and Tau Phosphorylation at Multiple Alzheimer’s Disease-Related Sites.” PLoS ONE 6(5): e19264, May 2011.
- [12] Dennis J McKenna,”Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges.” Pharmacology & Therapeutics, Volume 102, Issue 2, 2004, pp. 111-129.
- [13] Berrougui, Hicham, et al. “Protective effects of Peganum harmala L. extract, harmine and harmaline against human low-density lipoprotein oxidation.” Journal of Pharmacy and Pharmacology, Volume 58, Issue 7, July 2006, pp. 967–974
- [14] Liu, Xin, et al. “Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling.” Biochemical and Biophysical Research Communications, Jul 2017, pp. 489(3):332-338. doi: 10.1016/j.bbrc.2017.05.126
- [15] Dos Santos, Rafael G., and Jaime E.C. Hallak. “Effects of the Natural β-Carboline Alkaloid Harmine, a Main Constituent of Ayahuasca, in Memory and in the Hippocampus: A Systematic Literature Review of Preclinical Studies.” Journal of Psychoactive Drugs, vol. 49, no. 1, Dec 2016. 02791072.2016.1260189
- [16] Dakic Vanja, et al.”Harmine stimulates proliferation of human neural progenitors.” PeerJ, 2016 Dec 6;4:e2727. doi: 10.7717/peerj.2727
- [17] Wu, Ying-Hui, and Dick F. Swaab. “The human pineal gland and melatonin in aging and Alzheimer’s disease.” Journal of Pineal Research, Dec 2004.
- [18] Dean, Jon G., et al. “Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain.” Scientific Reports, Jun 2019, 9333
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